All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

This important study explores the conserved role of IgM in both systemic and mucosal antiviral immunity in teleosts, challenging established views on the differential roles of IgT and IgM. The ...

Gasdermin D and gasdermin A3 are pore-forming proteins and executors of pyroptosis, however, the process of oligomer formation of the transmembrane pore structure has not yet been elucidated.

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

The findings could guide future efforts to ... Jan. 17, 2025 — A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain ...

The integration of cytokines into stem cell and organoid research has significantly advanced drug discovery by enabling more ...