Researchers have discovered that a protein complex that helps fight cancer cells also slows the growth of tuberculosis—a ...

This valuable study uses robust time-dependent microscopy assays to show that during HIV-1 infection, the viral accessory protein Vif causes cell cycle arrest during metaphase and not G2/M as ...

To perform that screening, they used the CRISPR/Cas9 gene-editing technology to inactivate genes ... cells that survive through controlling bacterial growth." They found 259 knockout genes that ...

Mice constitute the most widely used model since their retinal structure is similar to humans and they can easily provide knock-out/-down models ... Comparison of CRISPR/Cas9 nucleases, base editors, ...

we have used CRISPR-cas9 to knock out TLR4 and TLR9 of A20 cells and repeated the experiments, as suggested. We chose TLR4- and TLR9- knockout A20 cell lines instead of TLR-deficient mice because a ...

Transgenic and gene-targeted mouse models enable Mayo Clinic ... Services include: CRISPR-Cas9-mediated editing of genes of interest in fertilized eggs to generate knockout and knockin animal models ...

Editas Medicine announced proof-of-concept data for a gene-editing approach for sickle cell disease that doesn't need a stem ...

Cancer continues to be a formidable challenge globally, with traditional drug discovery methods focusing on cytotoxic agents and targeted therapies altering the landscape of cancer prognosis and ...