For decades, people on certain medications have had to avoid grapefruit due to its interference with drug metabolism. Now, ...

Supplement and medication interactions occur when active compounds in supplements alter the way a drug is absorbed, ...

such as the cytochrome p450 (CYP) and others, that process many types of medications. This is called metabolism. It also has a way to get rid of drugs, usually though your urine. Other drugs may ...

AIMS: To explore the potential for drug interactions on quetiapine pharmacokinetics using in vitro and in vivo assessments. METHODS: The CYP enzymes responsible for quetiapine metabolite formation ...

Cytochrome P450 enzymes are critical players in the metabolism of a variety of pharmaceuticals, particularly within the liver, where they catalyze the oxidation of numerous drugs. The induction of ...

A number of studies have highlighted that ethnicity is an important factor influencing the genetic variability of some CYP450 enzymes and that human adaptation could have a role in shaping the ...