such as the cytochrome p450 (CYP) and others, that process many types of medications. This is called metabolism. It also has a way to get rid of drugs, usually though your urine. Other drugs may ...

For decades, people on certain medications have had to avoid grapefruit due to its interference with drug metabolism. Now, ...

AIMS: To explore the potential for drug interactions on quetiapine pharmacokinetics using in vitro and in vivo assessments. METHODS: The CYP enzymes responsible for quetiapine metabolite formation ...

The research of D. Fernando Estrada, PhD, associate professor of biochemistry, has been recognized by the American Society for Pharmacology and Experimental Therapeutics (ASPET).

The primary culprit behind these drug interactions is a group of chemicals ... One key enzyme is cytochrome P450 3A4, or CYP3A4. As the furanocoumarins in grapefruit are broken down in the body ...

A number of studies have highlighted that ethnicity is an important factor influencing the genetic variability of some CYP450 enzymes and that human adaptation could have a role in shaping the ...