NORTHAMPTON, MA / ACCESS Newswire / April 1, 2025 / In 2006, Tomas Cihlar knew all too well that despite initial successes ...

The FDA granted priority review, with a decision expected by June 19, 2025. LEN represents a novel class of HIV therapies by targeting the viral capsid, a multifunctional protein essential for HIV ...

This involves the HIV-1 protease (a viral enzyme), that cuts up Gag into six smaller proteins including the capsid protein ...

The Zika virus builds tiny tunnels, called tunneling nanotubes, to stealthily transport material needed to infect nearby cells, including in placental cells, according to a team of researchers from ...

Krol, M. A., et al., RNA-controlled polymorphism in the in vivo assembly of 180-subunit and 120-subunit virions from a single capsid protein. Proceedings of the National Academy of Sciences of the ...

Latus’ other lead gene therapy uses its AAV-Ep+ capsid to target ependymal cells as well as neurons. Ependymal cells secrete proteins into the cerebrospinal fluid. Co-opting this function ...

The dengue virus has a roughly spherical structure. It is composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins. After infecting a host cell ...

how do the capsid proteins identify their genome for encapsidation, and 3) are specific nuclear sites used as 'workbenches' to couple viral DNA replication with capsid assembly. Our study of human ...

Viral proteins with sugars attached to them are ... These viruses have only the capsid surrounding their genetic material. A virus budding from a host cell membrane. This sequence of steps forms ...

Lenacapavir 463.5mg/1.5mL (309mg/mL); soln for SC inj; preservative-free. Lenacapavir is a multistage, selective inhibitor of HIV-1 capsid function that directly binds to the interface between ...