A dual-drug hydrogel using dexamethasone and kartogenin supports cartilage repair by controlling inflammation and promoting ...

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

Structure-based drug design articles from across Nature Portfolio Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound ...

In this issue of Nature Chemical Biology, Challis and coworkers 1 present an alternative paradigm for natural-product discovery in which the 'chance' component is largely abated.

Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.

As summer kicks into full gear and people are spending more time outside, there's one thing on many people's minds - ticks.

All of these effects depend on the puzzle-like system that is molecular biology. The structure of a neurotransmitter such as dopamine determines which part of the cells it can fit into and what effect ...

On the basis of model imidazole inhibitors of cytokine release, a series of novel pyridinyl pyrimidine derivatives was prepared and tested on their ability to inhibit the release of tumor necrosis ...