DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

Scientists have created an artificial RNA system that can copy itself using simple building blocks and temperature changes.

In this episode presented by Eclipsebio, BioSpace's head of insights Lori Ellis discusses mRNA and srRNA with Andy Geall of Replicate Bioscience and Alliance for mRNA Medicines, and Pad Chivukula of ...

May 22, 2025 — Researchers have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through lice rather than ...

Wave claims this is the first clinical data with a therapeutic RNA-editing drug in humans, an achievement that boosted its stock, even as the news also emerged that Takeda had pulled out of a ...

The heterogeneity of isoform level m 6 A RNA methylation in single cells is unclear. The authors characterize m 6 A at both single-cell and isoform level through ONT long-read sequencing on single ...

Messenger RNA (mRNA) vaccines hold promise for creating new and improved immunizations; however, their delivery is challenging in terms of compliance, reactogenicity, cost and scalability.

A solid-phase DNA-encoded library (DEL) was studied for binding the RNA repeat expansion r(CUG)exp, the causative agent of the most common form of adult-onset muscular dystrophy, myotonic dystrophy ...

实验证实，WWP1缺失会损害DNA损伤修复因子的募集，降低修复效率，从而增强AML细胞对化疗药物的敏感性。 这些发现揭示了WWP1-JARID1B轴通过调控染色质修饰和DNA修复影响AML化疗耐药性的新机制。 创新性总结： ...