Antibiotics are a double-edged sword—they should be as toxic as possible to pathogenic bacteria while being harmless to the cells ... target IspD, a protein that is not addressed by any drug ...

In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria ... a drug that targets some part of the OPG pathway might sensitize the cells to existing ...

An international research team led by the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has now developed drug candidates that achieve precisely that. The new molecules target a ...

The team found that four related proteins from different bacterial species all adopted a similar shape, each carrying a hollow barrel, implying that they may behave as transport channels if inserted ...

Tuberculosis is a serious global health threat that infected more than 10 million people in 2022. Spread through the air and ...

Microbes that reside peaceably in the nasal passageways and on the skin can be harnessed for taking drugs to target cells.

Consequently, there is a pressing need for new drugs, preferably with novel modes of action to avert the problem of cross-resistance. Several new targets have been proposed, including proteins ...

Raman figured out a way to control when the bacteria, after it has been intravenously injected, invades the cancer cells and delivers the therapy. This greatly improved the ability to target the ...

The search for new tuberculosis drug targets under traditional laboratory methods has historically proven to be arduous and ...