Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients ...

Thousands of bacterial and other microbial species live in the human gut, supporting healthy digestion, immunity, metabolism ...

Thousands of bacterial and other microbial species live in the human gut, supporting healthy digestion, immunity, metabolism ...

1 2 In a healthy liver, HSCs reside in the space of Disse in between hepatocytes and liver sinusoidal endothelial cells (LSEC). On liver injury, HSCs undergo activation and differentiation into ...

Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology in ...

Pseudotime and CytoTRACE analyses indicated that C0 cells represent a late-stage, low-stemness state with epithelial-mesenchymal transition (EMT)-like features. Taken together, these findings reveal a ...

Single cells are typically typed by clustering into discrete locations in reduced dimensional transcriptome space. Here we introduce Stator, a data-driven method that identifies cell (sub)types and ...

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China Center of Materials Science and Optoelectronics ...

We thank Bruce Vallance for their gift of Il18 −/− mice. NJW was supported by both an Ontario Graduate Scholarship and Canadian Graduate Scholarship, and this project was funded by Grants from the ...

Small cell lung cancer (SCLC), accounting for 10–20% of lung cancers ... highlighting the critical need for reliable biomarkers and innovative therapies. Delta-like ligand 3 (DLL3), a Notch signaling ...