When it comes to fitness, most people focus on macros, supplements, and training intensity—but there’s a crucial molec ...

WGCNA identified a gene module linked to cuproptosis, crucial for pathways like cell cycle regulation, citrate cycle (TCA cycle), and DNA replication. The novel risk model stratified patients into ...

Department of Biological Sciences, The University of Texas at Dallas, United States; Department of Urology, University of Texas Southwestern Medical Center, United States; ...

Our results suggest that central metabolic pathway - TCA cycle appears to be more sensitive to moderate-intensity physical activity (as reflected by the lowering of myocardial citrate concentration) ...

While this research focused on αKGDH, other enzymes within the TCA cycle may also be affected, necessitating further investigation. Beyond their immediate findings, the researchers’ use of ...