Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD ...

cDNA microarrays are capable of profiling gene expression patterns of tens of thousands of genes in a single experiment. DNA targets, in the form of 3´ expressed sequence tags (ESTs), are arrayed ...

“We demonstrated that gene-expression profiling is a robust technology for the diagnosis of hematologic malignancies with high accuracy,” commented joint-lead researcher Torsten ...

[4] This review is centered on PC biomarker development accomplished through microarray-based mRNA and miRNA gene expression profiling.

Researchers at Fred Hutch and MD Anderson discovered RNA Polymerase II on histone genes as a biomarker for cancer ...

Short interval circulating tumor DNA (ctDNA) kinetics as a predictor of tumor response in patients with gastrointestinal (GI) cancer receiving immune checkpoint inhibitor (ICI)-based treatment. This ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone ...

How do bacteria—harmless ones living in our bodies, or those that cause disease—organize their activities? A new study, ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

"He took these biopsies and created patient-derived xenografts, and then we went ahead and did epigenetic profiling and gene expression profiling of these samples," Singh said. "Then we compared ...