This image shows the replication cycle of HIV/SIV. The virus replicates in the body's own CD4+ T helper cells. In doing so, it introduces its own genetic information into the DNA of the host cell.

Since HIV’s discovery in the 1980s, scientists have come a long way in understanding the different steps required for its assembly and ... cells and what role the lipid envelope plays in HIV ...

Researchers from the Max Planck Institute of Biochemistry have discovered the mechanism behind an important step in the life ...

or a ‘central DNA flap,’ as a component of HIV nuclear import. The retroviral replication cycle requires that retroviral nucleic acids integrate into the cellular DNA of the host cell.