Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Immunotherapy, which uses programmed immune cells to selectively destroy cancer cells, has transformed cancer treatment.

School of Physics and Electronics, Key Laboratory of Low-dimensional Quantum Structures and Quantum Control of the Ministry of Education, Institute of Interdisciplinary Studies, Key Laboratory for ...

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the aging process and are resistant to ...

Salk Institute researchers found that regulating bile acids—specifically reducing harmful ones and increasing UDCA—can enhance T cell function and potentially make immunotherapy more effective for ...

The team demonstrated this both in mouse liver cancer cells and in several human cancer cell lines. The findings are published in the journal Nature Metabolism. However, when the researchers ...

Moreover, LSEC induce functional T cell exhaustion under low dose chronic stimulation conditions. Thus, LSEC critically regulate the balance between preventing/limiting liver injury and permitting ...

Long classified as a subset of common liver cancer, FLC should be considered ... That is the true origin of the disease. FLC tumor cells essentially have a molecular imbalance: too many catalytic ...

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor’s cancerous cells influence their surroundings ... “Traditional therapies target one molecule in the tumor ...

A new report points to a notable increase among U.S. women under 50. Experts point to a few likely causes. By Nina Agrawal Siobhan Donovan was a runner who ate her vegetables, didn’t smoke and ...

Immunotherapy, which leverages the immune system to target osteosarcoma cells, shows promise. This review summarizes the biological characteristics of osteosarcoma, mechanisms of pulmonary metastasis, ...