potentially first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme ...

Metabolic disorders such as iron overload, glycolysis, insulin resistance, lipid dysregulation, and glutaminolysis can induce senescence, ferroptosis, inflammation, and fibrosis to promote the ...

Different plant-derived extracts and essential oils demonstrated antifungal activity, interfering in particular with the fatty acid homeostasis pathway. Resurgence of interest and increasing ...

Want to apply for Canada PR? The country is set to introduce four new permanent residency (PR) pathways in 2025, even as the government plans to reduce its PR targets from 485,000 to 465,000, ...

potentially first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme ...

Bitopertin is an investigational agent and is not approved for use as a therapy in any jurisdiction worldwide. Disc obtained global rights to bitopertin under a license agreement from Roche in May ...

The iron lung, conceptualized in the late 1920s, was most notably the first line of defense against polio during the epidemics that occurred between 1948 to 1955. The device saved the lives of ...

Last spring, when the sculpture — briefly titled “Steel Horse” and then “Pegasus” by the artist, but popularly known as Iron Horse — was extricated from a concrete pad in a cornfield ...

Native levels of Wag31 are critical for the maintenance and distribution of membrane lipids. Both depletion and overexpression of Wag31 perturbs lipid homeostasis, leading to the formation of ...

We quantitatively compared seven OER pathways applicable to both the adsorbate evolution mechanism (AEM) and the lattice-oxygen-mediated mechanism (LOM) families, elucidating how iron significantly ...