New findings show that the stage of normal cell development at which B cells transform into leukemic cells impacts treatment ...

Lu wondered whether differences across individual HSC were intrinsic or influenced by their environment. To test this, the researchers infected HSC with lentivirus carrying unique genetic barcodes to ...

A new study shows that the stage of normal cell development at which B cells transform into leukemic cells impacts treatment ...

Innate lymphoid cells (ILCs) are immune cells that belong to the lymphoid lineage but do not express antigen-specific receptors. These cells have important functions in innate immune responses to ...

Innate lymphoid cells (ILCs) participate in tissue homeostasis, ... “Effector differentiation downstream of lineage commitment in ILC1s is driven by Hobit across tissues. ...

Scientists at St. Jude Children’s Research Hospital and University Health Network showed that the stage of B-cell development ...

In the current dominant model of haematopoiesis, T cells are thought to arise from lymphoid-restricted common lymphoid progenitors, and myeloid cells (including granulocytes and macrophages, found ...

Sometimes, these precursor cells acquire genetic mutations that prevent their differentiation and promote growth of the precursors. A buildup of these mutant precursors is known as leukemia. Potent ...

In a marginal-zone B-cell lymphoma, ... Lineage involvement of stem cells bearing the Philadelphia chromosome in chronic myeloid leukemia in the chronic phase as shown by a combination of ...

A phase 1 adaptive dose-escalation study to evaluate the tolerability, safety, pharmacokinetics, and antitumor activity of ADCT-402 in patients with relapsed or refractory B-cell lineage non Hodgkin ...

New knowledge on lymphoid cell maturity could lead to more effective IBD therapies. ScienceDaily . Retrieved April 19, 2025 from www.sciencedaily.com / releases / 2022 / 04 / 220415163754.htm ...