Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

Macrophage cells take in and digest a large amount of nutrients to aid in the regular function of the immune system. To break ...

Lysosomes are subcellular organelles that are mainly responsible for degradation of proteins internalized by cells by endocytosis and phagocytosis. Upon uptake, proteins and soluble components ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...

A new study led by Harvard biologists describes how some sea slugs consume algae and incorporate their photosynthetic ...

MSD has agreed to pay up to $610 million to acquire Caraway Therapeutics, a Cambridge, Massachusetts biotech focusing on neurodegenerative disorders and rare diseases. The big pha ...

This review article provides a comprehensive overview of stress granules (SGs) —membraneless organelles formed in response to ...

This was likely due to impaired lysosome function, demonstrated by accumulation of LAMP1 positive vacuoles that exhibited impaired cargo degradation and lack of normal acidity. We next showed that ...

University of Virginia scientists discover new cell organelle called "hemifusome" that helps manage cellular recycling.

Some two dozen biotech developers of PROTACs, molecular glues and other types of protein-degrading drugs have sprung up over ...

Findings could help explain the links between macular degeneration and cardiovascular disease, which both worsen with age.