RNA-based therapeutics are gaining traction due to advancements in delivery technologies, despite historical challenges with ...

Psychiatric disorders challenge us deeply. At the University of Arizona, researchers dissect their molecular roots, focusing ...

The kit purifies all sizes of RNA, from large mRNA and ribosomal RNA down to microRNA (miRNA). The RNA is preferentially purified from other cellular components such as proteins, without the use ...

Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...

At the transcriptional level, lncRNAs can recruit chromatin-modifying complexes to specific genomic loci, while post-transcriptionally, they can affect mRNA splicing, stability, and translation.

Additionally, we analyzed these genes and the lncRNA-miRNA-mRNA co-regulatory network in high- and low-IMF femoral biceps groups. Results: We identified 11,529 mRNAs (747 differentially expressed), ...

The integrated analysis of miRNA-mRNA interactions highlighted miRNAs as central regulators of defense mechanisms in WY, particularly at later stages of infection. These miRNAs targeted genes involved ...

Safra Campus, Jerusalem, Israel Objective Both non-alcoholic fatty liver disease (NAFLD) and the multitarget complexity of microRNA (miR ... repress the expression of target mRNA transcripts, ...

Methods We collected a total of 199 donor liver tissues and performed ASA chip, 850K chip, mRNA-seq and miRNA-seq analysis. PTDM was defined according to the American Diabetes Association’s diagnostic ...

The following is a summary of “Identification of hypertension subtypes using microRNA profiles and machine learning,” ...