Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...

Researchers at the Francis Crick Institute and UCL have shown that genetic messages are misplaced in nerve cells in a model ...

Despite widespread use during Covid-19 pandemic, mRNA vaccines have become a subject of growing political and social debate ...

A more effective vaccine technology may be on the horizon. In a new study in mice, researchers from the University of ...

The safety of approved mRNA vaccines is well-established and, as with other vaccines, continues to be monitored by multiple ...

Further, we propose a L0-regularized singular value decomposition (L0-SVD) to identify miRNA-gene joint modules from the predicted regulatory network. We test our method on the matched miRNA and mRNA ...

The mRNA and protein levels of miR’s biotargets were monitored sequentially after dosing up to 24 h. ... MicroRNA-mediated immune modulation as a therapeutic strategy in host-implant integration.

Both mRNA and isomiR read counts tables were normalized for size factors using DESeq2 v 1.44.0 . Then, after gene length normalization, the mRNA table was transformed to fragments per kilobase of ...

Benzo(a)pyrene (BaP), a carcinogen prevalent in high-temperature processed foods, activates the aryl hydrocarbon receptor (AhR) and induces liver pyroptotic injury. MicroRNAs regulate mRNA expression ...

Moderna’s mRNA vaccine reaches its final phase. Here's how it works. The biotech firm's leading candidate has just entered phase three clinical trials in the U.S. Find out why this vaccine ...