Neonatal lupus skin lesions often appear in the first few weeks of life, but may be present at birth. Cutaneous lesions are often erythematous lesions, raised or flat, sometimes with fine scale.

The diagnosis should be suspected based on the maternal history of anti-Ro/La antibodies, a previous child with NLE, or autoimmune disease, especially photosensitivity, dry eyes, and dry mouth. It ...