The 49ers are riding a tow game losing streak into Week 17. They are poised to increase it to three in their matchup with the Lions. Here are three reasons why the 49ers will lose to the Lions.

The draft, the annual rite of spring where The Faithful demand an offensive lineman with the first pick and Kyle Shanahan takes another position. Might as well ...

The 49ers lost defensive tackle Javon Hargrave early with a torn triceps. Middle linebacker Fred Warner has played with an ...

The San Francisco 49ers have placed T Trent Williams on the Injured Reserve list, signed OL Matt Hennessy to a two-year deal ...

Charvarius Ward will join the list of 49ers missing Monday night’s game ... Ward and Cook lost their first-born daughter unexpectedly at 23 months old. Ward missed three games in the wake ...

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

The Detroit Lions and San Francisco 49ers have released their final injury reports of the week ahead of their Monday night showdown in Week 17 and there are a total of six players ruled out and ...

The injury report for the Detroit Lions (13-2) heading into their matchup versus the San Francisco 49ers (6-9) has five players. The 49ers (6-9) currently have 15 players listed on this week's ...

The San Francisco 49ers are prepping for Week 17 against the Detroit Lions on Monday Night Football. What they're not prepping for is a playoff push in January. At 6-9, Kyle Shanahan and the 49ers ...

At Levi's Stadium on Monday, Amon-Ra St. Brown and the Detroit Lions face George Kittle and the San Francisco 49ers in a matchup between two excellent pass-catchers, starting at 8:15 p.m. ET.