Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer ...

The team is optimizing the cancer genome analysis system to integrate it into CRC diagnosis and tailor treatments based on ...

A recent high-throughput study shows that some types of cancer are associated with mutations in a specific proto-oncogene or in a specific pair of proto-oncogenes (Thomas et al., 2007).

Researchers from Fujita Health University, Japan, uncover specific gene mutations and mechanisms that may contribute to the ...

For instance, one 2016 study reported that a handful of synonymous mutations in the KRAS oncogene changed a rare glycine-encoding codon into a commonly used one, potentially accelerating translation.

Our validation studies revealed mutations in most of the oncogenes analyzed, and the mutation frequency was consistent with previous reports. We also found new low-frequency mutations in our tumor ...

Researchers used mutational analysis to identify gene mutations that may drive carcinogenesis in colorectal tumors with high ...

Bacteria could be engineered to detect and respond appropriately to various oncogenic mutations, or even difficult-to-treat infections like Clostridium difficile. Worthley sees this potential to marry ...

Mutations in the oncogene KRAS are widespread in several human cancers, including pancreatic ductal adenocarcinomas (92%), colorectal carcinomas (49%) and lung adenocarcinomas (35%). These mutations ...

Operationally, mutated proteins that induce the development of the leukemic phenotype (oncogenes ... Additional examples are the mutations detected in the kinase growth factor receptors Kit ...

This previous feature affects how the disease develops after acquisition of oncogenic mutations. Read the full story here.