Our expert speaker will explore the need to progress from the one-assay-one-gene paradigm, how to include quality control ...

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

The first human trial of insulin-producing cells that have been gene-edited to evade immune attack is a success so far. The cells have survived and produced insulin for a month after being ...

This complex process, known as gene expression, determines which proteins we make and whether we make them in the correct amounts, crucial work given that proteins play a role in virtually every a ...

Trained on data from over 1.3 million cells, the model can predict gene expression in unseen cell types with high accuracy. It has already uncovered mechanisms driving a pediatric leukemia and may ...

The same is now possible in gene editing. Rather than employ separate tools for editing genes and regulating their expression, these distinct goals can now be combined into a single tool that can ...

The cDNA libraries, constructed from PCR products, were sequenced using the BGISEQ-500/MGISEQ-2000 system (BGI-Shenzhen, China). Quality control and data cleaning were performed using Fastp. Reference ...

hirsutum phytochrome A1 gene (PHYA1) resulted in a substantial improvement in ... between homozygous and hemizygous alleles at a particular locus. Quantitative real-time PCR (qPCR) combines ...