Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this ...

Hoffmann-LaRoche Ltd. Read the study: “G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation,” Science. DOI: : 10.1126/science.adt1978 ...

Over the past three decades, this detailed work has led to remarkable insights into the individual reaction steps involved in the workings and assembly of the T4 replisome 18. Sacrificing the ...

GINS1 is correlated with a poor prognosis in numerous cancers including liver hepatocellular carcinoma (LIHC). Here, efforts have been made to explore the function and underlying mechanism in LIHC ...

Aging is a prominent risk factor for many neurodegenerative disorders, such as Alzheimer’s disease (AD). Alzheimer’s disease is characterized by progressive cognitive decline, memory loss, and ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

School of Life Sciences, University of Warwick, Coventry CV4 7AL, U.K.