Objective Both belimumab and telitacicept are recognised blockers for B lymphocyte activation, both of which have been approved as add-on therapies for SLE in China. The aim of this study is to ...

The Food and Drug Administration (FDA) has approved Monjuvi ® (tafasitamab-cxix), in combination with lenalidomide and rituximab, for the treatment of adult patients with relapsed or refractory (R/R) ...

Roche and Genentech have announced outcomes from the randomised, multi-centre, international Phase III SUNMO trial for those ...

Background Despite case series suggesting efficacy, controlled trials of anti-CD20 in lupus and lupus nephritis (LN) have not meet their primary endpoints (Arthritis Rheum 2012;64:1215 and ...

Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin's lymphoma and is curable in more than 60% of patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and ...

Rituximab has a mechanism of action that is completely different from those of conventional immunosuppressants, and previous retrospective observational studies have suggested the combination of ...

Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is a subset of antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis with distinct pathophysiological mechanisms, ...

The use of rituximab (RTX) significantly diminishes the humoral immune response to the recombinant herpes zoster vaccine (RZV) among patients with autoimmune rheumatic diseases (ARDs), according to ...

As we are over a year into the COVID-19 pandemic, we have made many forward strides in therapeutics. These treatments, such as monoclonal antibodies, have help mitigate the detrimental and often fatal ...

Objective To gain more insight into the dynamics of lymphocyte depletion and develop new predictors of clinical response to rituximab in rheumatoid arthritis (RA). Methods RNA-based next-generation ...

Following the 2021 re-release of Ubisoft's Scott Pilgrim vs. the World: The Game, the developers of TMNT: Shredder's Revenge are taking a crack at a brand new Scott Pilgrim game. It's called Scott ...