Under persistent oxidative stress (ROS), inflammation, virus infection and metabolic dysregulation, LIF transition into intermediate inflammatory lipofibroblasts (iLIFs) (18), leading to impaired ...

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...

Japanese researchers have generated lung cells directly from mouse tissue. These lung cells are called Alveolar Epithelial ...

In response to various inflammatory stimuli, lung endothelial and epithelial cells, alveolar macrophages and other inflammatory cells produce ROS that damage the lungs and initiate proinflammatory ...

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

UCLA researchers have successfully grown miniature lungs from stem cells—complete with their own functioning blood vessel ...

The cuboidal type II cells are involved in surfactant production, fluid transport and repopulation of the alveolar epithelium following injury.

Managing Upper and Lower Airway Diseases: The Role of Epithelial-Driven Inflammation This activity is supported by an independent educational grant from AstraZeneca Pharmaceuticals.

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease.

Pinot noir does a lot of heavy lifting in the world of wine. It is used to make popular light red wines in several acclaimed regions, from Burgundy, France, to Oregon’s Willamette Valley and all ...

Self-Sustained Regulation or Self-Perpetuating Dysregulation: ROS-dependent HIF-YAP-Notch Signaling as a Double-Edged Sword on Stem Cell Physiology and Tumorigenesis ...