The primary method of sequencing DNA — referred to as dideoxynucleotide sequencing, chain-termination sequencing or, more commonly, Sanger sequencing, after its inventor, Frederick Sanger 1 ...

Sanger sequencing continues to be an efficient and effective method for identifying known genetic variants, making it a good initial method for genetic tests. With resolution down to a single base ...

A new genomic study reveals how human populations adapted, survived, and diversified in the Himalayas, one of the most ...

An expert discusses how the PEACE III combination of radium-223 and enzalutamide represents an effective treatment option for the limited population of patients who reach first-line metastatic ...

Tyler Sandahl, PharmD, a clinical pharmacist at Mayo Clinic, explains that sequencing novel multiple myeloma therapies with CAR T-cell therapy is generally prioritized first for eligible patients, ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these ...

This paves the way for the "paired sequencing" of the bacteria-and-host "couple" on the single-cell level. In their study, the researchers applied their new method to 25 mutant salmonella species that ...

RNA sequencing refers to techniques used to determine the sequence of RNA molecules. It includes high-throughput shotgun sequencing of cDNA molecules obtained by reverse transcription from RNA ...