The primary method of sequencing DNA — referred to as dideoxynucleotide sequencing, chain-termination sequencing or, more commonly, Sanger sequencing, after its inventor, Frederick Sanger 1 ...

Sanger sequencing continues to be an efficient and effective method for identifying known genetic variants, making it a good initial method for genetic tests. With resolution down to a single base ...

Then, Sanger's terminator technique is replaced by sequencing either by synthesis or by ligation. (As a reference for the nonspecialist, a Primer on page 15 gives a glance at the inner workings of ...

"The scale at which we analyzed the amyloid peptides was unprecedented," said Ben Lehner of the Wellcome Sanger Institute.

Researchers have uncovered new patterns of DNA damage associated with specific chemotherapy drugs to guide cancer treatment for less effects.

Imagine that you want to know the plot of a movie, but you only have access to either the visuals or the sound. With visuals ...

For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues.

A new genomic study reveals how human populations adapted, survived, and diversified in the Himalayas, one of the most ...

An expert discusses how the PEACE III combination of radium-223 and enzalutamide represents an effective treatment option for the limited population of patients who reach first-line metastatic ...

Cancer is not a welcome diagnosis, but breakthroughs in genetic sequencing and immunotherapy are making some cancers easier ...