School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, the University of Dublin, College Green, Dublin 2 D02 PN40, Ireland Trinity Translational Medicine Institute, Trinity College ...

The team, publishing in the journal Advanced Science, used a new drug discovery screening platform technology, called the Transcription Block Survival (TBS) assay, which tests a huge number of ...

In the literature, different results have been reported. By using the LIVE/DEAD assay, Machado et al. (26) verified cytotoxicity in HepG2 and HUVEC (human umbilical vein endothelial) cells treated ...

The most well-known model is the two-chamber migration assay, also known as the transwell assay (Falasca ... and does it express known markers for the BEC type of interest? Also, while HUVEC are ...

with the protocol of the manufacturer using the dual luciferase assay kit from Promega (Madison, WI, USA). HUVEC cells were grown and co-transfected with 100 ng of a firefly luciferase reporter ...

Force measurement on a spheroid poses two formidable problems. First, current 3D finite element force reconstruction methods that have been designed for single cells in a non-linear material such as ...

Angiogenesis requires the temporal coordination of the proliferation and the migration of endothelial cells. Here, we investigated the regulatory role of microRNAs (miRNAs) in harmonizing angiogenesis ...