Stanford scientists have identified 380 key genetic variants that significantly influence cancer development, filtering ...

In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.

Stanford Medicine researchers sifted through thousands of single nucleotide mutations in DNA to identify fewer than 400 that are functionally associated with inherited cancer risk.

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

Thousands of single changes in the nucleotides that make up the human genome have been associated with an increased risk of ...

By Balambal Suryanarayanan CRISPR-Cas9 is a repurposed gene editing tool that allows scientists to cut, replace, and insert pieces of DNA in precise regions along the strand. Courtesy of NIH Image ...

The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...

Repeats Raise Risk. The more STR expansions a person carried, the higher their odds for AD (left). People with more repeat expansions tended to have worse tau pathology as per Braak stage (right).

Researchers developed an epigenetic editing approach to silence the PCSK9 gene, achieving long-term cholesterol reduction ...

Research from Umeå University paves the way for a quantitative data analysis method to study the cell division process in ...

Researchers around the world are working on new technologies to capture carbon from the atmosphere, but many approaches fall short on one key metric: their ability to scale. Nature, however, has ...