Nanoparticle characterization is vital for mRNA vaccine efficacy, ensuring safety and regulatory compliance in the ...

Exosomes, the small extracellular vesicles secreted by nearly all cell types, have emerged as powerful players in intercellular communication and potential biomarkers for disease diagnosis and therapy ...

Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD ...

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing ...

A high-quality genome assembly of Silene latifolia was generated by researchers at CNRS/Université Claude Bernard Lyon 1 and ...

To resolve this problem, we first 1) introduce five device-agnostic (DA) and seven device-related (DR) quantitative metrics, 2) using which we thoroughly characterize the effects of ViT ...

Typically, tissue samples, clinical biopsies and other native biological materials provide small quantities of total RNA, with mRNA constituting only 1-3% of this total. The EpiPlex kit's high ...

We constructed miniaturized autoantigen arrays to perform large-scale multiplex characterization of autoantibody responses directed against structurally diverse autoantigens, using submicroliter ...

After a primary test for RNA quality and integrity, the sequencing samples were finally sequenced on Novaseq 6000 sequencer (Illumina) with PE150 model. The raw sequencing data were mapped to the ...

At least some piRNAs are involved in transposon silencing through heterochromatin formation or RNA destabilization. Endogenous small interfering RNAs (endo-siRNAs), such as miRNAs, associate with ...

Being an integral player in RNA therapeutics, Alnylam’s drugs may be the first to come to mind. Patisiran was approved in 2018 for transthyretin amyloidosis (ATTR), a disease that affects multiple ...