This valuable manuscript provides convincing evidence that BK and CaV1.3 channels can co-localize as ensembles early in the biosynthetic pathway, including in the ER and Golgi. The findings, supported ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Hexarelin, a synthetic hexapeptide, has garnered attention in various research domains due to its intriguing biochemical ...

However, an easy way to reduce sodium levels naturally is by better management of sodium and potassium. In fact, here are some common foods that can naturally help reduce sodium levels.

SINGAPORE: To reduce sodium intake in Singapore, the Health Promotion Board (HPB) is pushing people to switch from regular salt to lower-sodium alternatives. More than one in three Singaporeans ...

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Low blood sodium, or hyponatremia, occurs when water and sodium are out of balance in your body. It can cause weakness, headache, nausea, and muscle cramps.

The bioavailability of pantoprazole when administered as a suspension in sodium bicarbonate solution and as the oral tablet was studied. In an open-label, randomized, two-period crossover study ...

Membrane proteins are proteins found in cell membranes, either at the surface or on intracellular organelles. Integral membrane proteins such as receptors and ion channels span the membrane ...

In the process of synaptic transmission, vesicle trafficking refers to the formation, intracellular movement and exocyotosis and endocytosis of synaptic vesicles.

If you're limiting your added sugar intake, diet sodas like Coke Zero and Diet Coke may appeal to you. This article explores how these drinks compare in terms of nutrition, flavor, and health effects.

Cellular membranes are, in general, impermeable to macromolecules (herein referred to as macrodrugs, e.g., recombinant protein, expression plasmids, or mRNA), which is a major barrier for clinical ...