In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of power ...

Energy-generating waves on the membranes of cancer cells may help to fuel disease progression. Disrupting the process could slow or halt cancer metastasis. Higher levels of the enzymatic waves ...

The scientists then found a 25% decrease in ATP, suggesting that cancer cells largely depend on these waves to fuel and execute their daily energy-intensive activities.

The enzyme MTH1 cleanses the cellular nucleotide pool of oxidatively damaged 8-oxo-dGTP, preventing mutagenesis by this nucleotide. The enzyme is considered a promising therapeutic target; however, ...