A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of ...

It is the first comprehensive cellular analysis of ALS, carried out using single-cell RNA sequencing in 14 patients and 14 ...

A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of ...

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Cancer cells alter the mitochondrial DNA (mtDNA), in turn causing mutations. Analysing this mechanism is a new breakthrough in the cancer research and treatment.

Nutrient access and metabolism regulate lymphocyte function, crucial in demanding environments like tumors. Dr. Delgoffe explores T cell metabolic defects in solid tumors and unveils strategies to ...

since hundreds of site-specific phosphorylations on key molecules for T lymphocytes are waiting for further study of novel functions and regulatory mechanisms. From the initial work based on studies ...

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...

Tumor-infiltrating lymphocyte functions, metabolic profiles ... could jump from cancer cells into T-cells. These transferred mitochondria carried functional errors in their DNA that interfered ...

Cytokines are proteins, peptides or glycoproteins secreted by lymphocytes and monocytes that ... cytotoxicity of tumour-specific CD8 + T cells. TILT-123 is an oncolytic adenovirus encoding TNFα ...

Lymphocytes are white blood cells that have important immune functions. The main populations of lymphocytes are B cells, T cells and natural killer (NK) cells. They are typically (although not ...