In a cohort of TRANSCEND FL, the chimeric antigen receptor T-cell therapy liso-cel showed a 95% overall response rate in relapsed marginal zone lymphoma, offering hope for improved patient outcomes in ...

CAR T-cell therapy targeting B-cell maturation antigen (BCMA) has become a game changer for patients with relapsed or ...

Mathieu Bennet: In B-cell cloning, single-cell isolation occurs at two crucial stages. First, during the initial screening phase, high-throughput isolation is required to analyze a broad antibody ...

This held true for all the investigated target antigens (CD33, CD123) expressed on MOLM13-TP53 isogenic cell lines and over several log2 fold ranges of E:T ratios (Fig. 1D,F,G). CAR T-cells targeting ...