The effects of VDR on Smad signalling were analysed by reporter assays ... In contrast, activation of VDR by paricalcitol reduced the stimulatory effects of TGF-β on fibroblasts and inhibited collagen ...

In the present study, we demonstrate that sGC stimulation interferes with transforming growth factor β (TGFβ ... inhibits SMAD-independent TGFβ signalling and reduces fibroblast activation and ...

The collagen positive area was quantified using the ImageJ software ... such as adriamycin-induced nephropathy to confirm the antifibrotic effect of RDV. The TGF-β/Smad signaling pathway is the major ...

Neuraminidase (NA) of IAV is able to activate latent TGF-β and the downstream TGF-β signaling pathway ... and 5-μm sections were stained with Masson’s trichrome reagent to demonstrate collagen. The ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

The maritime industry, a cornerstone of global trade, is undergoing a significant transformation through the adoption of digitalization and smart shipping technologies. As the industry navigates ...

This Agenda is a plan of action for people, planet and prosperity. It also seeks to strengthen universal peace in larger freedom, We recognize that eradicating poverty in all its forms and dimensions, ...