A new episode of Hoda Kotb's podcast, “Making Space,” is out featuring Christina Applegate and Jamie-Lynn Sigler who open up ...

In a heartfelt conversation on Hoda Kotb's Making Space podcast, Christina Applegate and Jamie-Lynn Sigler opened up about ...

Christina Applegate and Jamie-Lynn Sigler discuss differences in how they live with multiple sclerosis in an emotional ...

Christina Applegate and Jamie-Lynn Sigler share painful MS experiences on MesSy podcast, offering support and advice for others with similar struggles.

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars prepare to ...

Christina Applegate got emotional opening up about her struggle with multiple sclerosis, nearly four years after she was ...

Christina Applegate shared that she thinks her gastrointestinal symptoms are related to multiple sclerosis, explaining, "I get all the pain" from bowel movements.

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, I’ve been in the hospital upwards of 30 times from throwing up and ...

She now co-hosts a podcast about life with MS, called “MeSsy,” alongside actor Jamie-Lynn Sigler. Sigler, best known for her role on “The Sopranos,” was diagnosed at 20 but didn’t share ...

The Lonely Island just dropped a huge bombshell about one of their biggest tracks, revealing that Justin Timberlake had ...