The 49ers haven’t been shy about paying big bucks, and haven’t always received a good return on their investment.

The once stout 49ers defense allowed the Cardinals to score six touchdowns on them, capping off the year with a game that ...

The San Francisco 49ers' nightmare season has come to a close, capped off by a 47-24 loss to the Arizona Cardinals to end their season at 6-11. One player who has come under criticism is captain ...

In the last three games of the season, the 49ers defense gave up a whopping 116 points even though it had Nick Bosa on the ...

The 49ers' defense let them down as they gave up 242 yards and four touchdowns through the air to Cardinals star Kyler Murray ...

Tight end George Kittle and right tackle Colton McKivitz will suit up and play through injuries in the 49ers’ season finale ... Defensive end Nick Bosa was questionable with a knee injury ...

Watch highlights of San Francisco 49ers 2025 Pro Bowlers TE George Kittle, LB Fred Warner, DL Nick Bosa and FB Kyle Juszczyk from the 2024 NFL Season. San Francisco 49ers FB Kyle Juszczyk hauled ...

The San Francisco 49ers' season came to an end with yet another ... San Francisco defensive end Nick Bosa, who is one of the team's captains, admitted after the loss that it's hard to look players ...

The San Francisco 49ers suffered a crushing 12-6 ... Other important players like defensive end Nick Bosa (hip, oblique) and linebacker Dre Greenlaw (achilles, knee) were also deemed questionable.

George Kittle disagreed with defensive end Nick Bosa's comments after following up their Super Bowl loss with another disappointing season.

The San Francisco 49ers fired defensive coordinator Nick Sorensen after just one disappointing season, a person familiar with the decision told The Associated Press. The person spoke on condition of ...