Christian McCaffrey is dealing with another long-term injury again. The San Francisco 49ers running back went down with a knee injury during the second quarter of the team's "Sunday Night Football ...

The Los Angeles Rams wide receiver Nacua had an incredible moment in the first quarter of his team’s divisional contest against the rival San Francisco 49ers ... Ward’s helmet to secure ...

Ahead of this past weekend, San Francisco 49ers general manager John Lynch insisted he found suggestions claiming the club could potentially listen to trade offers for head coach Kyle Shanahan ...

Remember the San Francisco 49ers’ shootout in New Orleans in 2019 — the game in which Jimmy Garoppolo and Drew Brees combined for nearly 700 passing yards and nine passing touchdowns ...

SANTA CLARA, Calif. — The San Francisco 49ers still have plenty of talent. They still have plenty of good coaches. The missing element in their disappointing season so far, the team decided in t ...

Rookie running back Isaac Guerendo left late in the fourth quarter of the 49ers' 38-13 win over the Chicago Bears with a foot injury, according to head coach Kyle Shanahan. The 49ers will learn ...

His second target of the day was a seven-yard touchdown pass to the left corner of the end zone to cap off the 49ers five-play, 70-yard opening drive. To get the fans really hyped, Jennings celebr ...

The only real interesting moment of the San Francisco 49ers’ business-like 38-13 blowout win over the Chicago Bears on Sunday came in the fourth quarter, when a minor skirmish broke out after ...

San Francisco 49ers rookie running back Isaac Guerendo sustained a foot injury and was questionable to return in Sunday's matchup with the Chicago Bears. More News: Chargers Make Game-Time ...

A week after the Buffalo Bills blew them out, the San Francisco 49ers had their own chance to play bully. Hosting the Chicago Bears in Chicago’s first game since firing head coach Matt Eberflus ...

The San Francisco 49ers finally looked like Super Bowl contenders in Sunday’s blowout win over the hapless Chicago Bears. But even with the victory, the Niners’ chances to reach the playoffs ...