San Francisco 49ers quarterback Brock Purdy reportedly suffered a nerve issue in his right elbow late in Monday's 40-34 loss against the Detroit Lions and will undergo further testing on Tuesday ...

Tensions were high in the first quarter of a Monday night game between the Detroit Lions and the San Francisco 49ers. The Lions ... slapped the player in the helmet. Joseph and Jennings were ...

With last place in the NFC West clinched, the 49ers know exactly which teams they will face during the 2025 NFL season. The order in which they face them, however, remains to be seen. San ...

Brock Purdy threw for a career-high 377 yards and three touchdowns as the San Francisco 49ers fell to the Detroit Lions 40-34 at Levi's Stadium on Monday Night Football. Purdy also threw two ...

The Detroit Lions technically didn’t need to win Monday night’s matchup with the San Francisco 49ers, begging the question of whether head coach Dan Campbell would pull his starters at some ...

The 2024 season hasn't gone as planned for the San Francisco 49ers (6-9), but they'll still have a chance to play spoiler on Monday Night Football in Week 17 when they host the Detroit Lions (13-2).

The Detroit Lions scored on five consecutive drives in the second half to pull away for a 40-34 win over the host San Francisco 49ers on the final "Monday Night Football" matchup of the season.

The Lions (14-2) took down the San Francisco 49ers (6-10) 40-34 at Levi's Stadium in a high-scoring win. Detroit got a win on the same field where their 2023 season came to an abrupt end one game ...

The Detroit Lions are expected to play their starters on Monday Night Football against the San Francisco 49ers, despite the game being a dud. The result is essentially meaningless. "We’re going ...

The San Francisco 49ers and Arizona Cardinals play on Sunday, Jan. 5 at the Cardinals' State Farm Stadium in a game on the NFL Week 18 schedule. Which team will win the NFL Week 18 game?