University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their ...

the virus is never eliminated from the body, as it integrates into the genome of infected host cells and has several immune evasion strategies. These include antigenic variability, the structure ...

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...