Overall, screening of lipid distribution patterns revealed distinct inflammation-induced changes in the OVLT, highlighting the prominent role of lipid metabolism in brain inflammation. Moreover, known ...

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD ...

Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...

A new study reveals that increasing levels of apolipoprotein M (ApoM) may slow or prevent the progression of age-related macular degeneration (AMD), a major cause of blindness in older adults.

Findings could help explain the links between macular degeneration and cardiovascular disease, which both worsen with age.

Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

Cellular membranes are, in general, impermeable to macromolecules (herein referred to as macrodrugs, e.g., recombinant protein, expression plasmids, or mRNA), which is a major barrier for clinical ...