Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Since AlphaFold was first launched in 2021 ... big increase for antibody-antigen interactions and can decipher protein-ligand interactions that – according to a paper in Nature – outperforms ...

For example, to activate G-protein-coupled receptors (GPCRs), a common but challenging target class for antibodies, antibody binding needs to mimic natural ligand binding, or bind multiple ...

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and ...

‘Recent advances in deep learning and generative AI, particularly the success of AlphaFold in protein structure prediction, motivated us to explore these methods for chromatin structure prediction.’ ...

Researchers have been developing perovskite solar cells since 2009, in part because they’re easy to make. However, it’s challenging to produce perovskite cells as robust as the silicon ones that ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cable bacteria are centimeter-long ...

This study shows that the AI models, such as Pro-PRIME, can not only guide the evolution of protein thermal stability, enzymatic activity, and ligand affinity but also enable to develop the mutants ...