This article explores common challenges faced by flow cytometry users, such as fluorochrome selection, the utility of tandem ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Vivace Therapeutics Inc. closed a $35 million series D round led by RA Capital Management, an existing investor, and including other backers already on board: Canaan Partners and Cenova Capital.

A fast and affordable AI-enabled microfluidic cytometer could have important applications in low-resource settings.

(8) In this intact approach, ADCs are enriched from plasma matrix with immunocapture, followed by elution from beads before LC-MS (liquid chromatography–mass spectrometry) analysis. For the ...

The team incubated unpurified whole blood samples with beads coated with anti-CD4 + antibodies, which allowed them to bind specifically to CD4 + T cells in the sample. The sample was then passed ...

Enzyme-linked antibodies (or ligand binding proteins) are used to bind an analyte on a solid substrate, and convert a colourless reporter molecule to a coloured or luminescent product for detection.

The percentage of panel-reactive antibodies (PRAs) can be determined by calculating the percentage of beads that react positively with patient sera. Figure 2 shows schematic histograms of positive ...

Retinal genomic DNA (gDNA) was digested with MseI, DdeI, Alul, MboI, incubated with RNase III with/without RNase H and immunoprecipitated with S9.6 antibody/protein G beads. Retinal nuclear lysates ...

Scientists at UMC Utrecht have developed a new technology to efficiently isolate a specific subset of gut bacteria from fecal samples that are recognized by IgA antibodies. These "IgA-coated" bacteria ...

Acetylation at lysine residue in a protein mediates multiple cellular biological processes, including tumorigenesis. This study aimed to investigate the acetylated protein profile alterations and ...