More importantly, this mechanism is not limited to a specific type of ataxia but extends across ataxias of various etiologies." More information: Chih-Chun Lin et al, Reduced cerebellar rhythm by ...

The primary cellular events and mechanisms underlying the disease are unknown. We found that mice lacking cystatin B develop myoclonic seizures and ataxia, similar to symptoms seen in the human ...

Neuronal atrophy early in a mouse model of spinal cerebellar ataxia 1 may represent an adaptive mechanism that restores the density of potassium channels in Purkinje neurons, thus normalizing ...