Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today ...

Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole, itraconazole, voriconazole and posaconazole) and protease inhibitors (e.g., atanazavir). INR: International ...

Further presentations covered the antifungal isavuconazole (Cresemba ®) and the antibiotic ceftobiprole (Zevtera ®). Dr. Marc Engelhardt, Chief Medical Officer of Basilea, said: “Invasive ...

Olorofim (F901318) is the first in a new class of orotomide antifungal agents intended to provide a new treatment option for serious fungal infections when the current armamentarium of azoles ...

The Manchester-based company said the new cash will help it to complete the late-stage development of olorofim, a novel oral antifungal for invasive aspergillosis and other serious fungal ...

When a medication works right, it boosts your health or helps you feel better. But a drug can bring on problems if it doesn't mix well with something else you put into your body, like another ...

Apr. 17, 2025 — A professor's casual hike in the High Sierra turned into a new elevation record for California's highest tree, the Jeffrey pine, which wasn't formerly known to grow at extreme ...

Aloe vera is a medicinal plant with antioxidant and antibacterial properties. Aloe vera benefits can include reducing dental plaque, accelerating wound healing, improving skin barrier function ...

Apr. 9, 2025 — A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new ... Apr. 7, 2025 — A study ...

particularly monotherapy—suggesting that combination therapy should be investigated as a strategy to mitigate antifungal drug resistance.

Fungal genomics is a scientific discipline that concerns the genome, encompassing the entire hereditary information, of fungi. Fungal genomics can, for example, be used to study fungal evolution ...

Future Microbiol. 2013;8(8):967-978.