Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today ...

Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole, itraconazole, voriconazole and posaconazole) and protease inhibitors (e.g., atanazavir). INR: International ...

The MIC values of the azole antifungals and 5-FC were defined as the minimum drug concentration at which visual growth was determined to be 50% relative to that of the growth control, known as MIC 50.

Geographic variations in species distribution and echinocandin and azole antifungal resistance rates among Candida bloodstream infection isolates: report from the SENTRY Antimicrobial Surveillance ...

The "azole" products (such as miconazole and clotrimazole) are all antifungal medications used for vaginal yeast infections. Prescription medications may be needed for more severe infections.

Genomic changes in the infectious yeast Candida tropicalis may play a role in its resistance to antifungals, according to a study published in PLOS Biology. The work, led by Guanghua Huang at ...

Further presentations covered the antifungal isavuconazole (Cresemba ®) and the antibiotic ceftobiprole (Zevtera ®). Dr. Marc Engelhardt, Chief Medical Officer of Basilea, said: “Invasive ...

The study demonstrates that this RNAi approach shuts down vital fungal genes, thereby inhibiting pathogen growth - a groundbreaking step in the development of new antifungal therapies. (Nanowerk News) ...