Cystic fibrosis (CF) is a life-threatening autosomal recessive disease affecting over 160,000 people worldwide. CF is caused by loss-of-function mutations in the CF transmembrane conductance regulator ...

They face a side that knocked them out of the CAF CL semi-final last year. With the draw conducted, Mamelodi Sundowns and Orlando Pirates can only play each other if they reach the CAF Champions ...

NKCC1 and KCC2 jointly regulate Cl − homeostasis in neurons and thus affect the function of the GABAergic system (Côme et al., 2020). In the early stages of development, because the expression level ...

To identify the counterion and clarify the proton-mediated gating mechanism of GtACR1, we investigate the Glu68 and Asp234 mutant proteins (E68Q, E68D, D234N, D234E, and E68Q/D234N) expressed in ...