A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

The Department of Health – Abu Dhabi (DoH), the regulator of the healthcare sector in the emirate, has announced the introduction of CASGEVY, the first CRISPR/Cas9 gene-editing therapy in the UAE.

In contrast, the CRISPR/Cas9 size range is 4000-5000 base pairs, sometimes requiring more than one AAV for its delivery (see image below). Although the ARCUS platform is completely applicable to ...

In cystic fibrosis, researchers have used CRISPR HDR-mediated knock-in to correct mutations in the CFTR gene in airway stem cells. For sickle cell disease, the FDA has approved a CRISPR/Cas9 therapy ...

The team first focused on a structural feature of the CRISPR Cas9 protein that is key to its success as a genome-editing tool; this structural feature is responsible for binding to the enzyme’s RNA ...

Beam Therapeutics said Monday that it used a form of CRISPR called base editing to correct, in several patients, a mutation that drives a debilitating lung condition that may affect tens of ...

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