Although only transiently expressed, the pre-BCR marks an important checkpoint in B-cell development and regulates diverse processes, such as proliferation, allelic exclusion of the second heavy ...

To assess B cell proliferation, purified B cells were labeled with eFluor670 or CFSE, stimulated with anti-IgM or LPS and analyzed for cell division by flow cytometric measurement of eFluor670 or CFSE ...

Mechanistically, bioenergetic assays and rescue experiments showed that mubritinib targets complex I of the electron transport chain, thereby impairing BTSC self-renewal and proliferation. Gene ...

In a dark coincidence, the researchers point to California's current catastrophe as a timely example of their recently published findings. "In that publication, fairly incredibly, we use the example ...

This guide explains why career goals matter, provides practical examples, and offers strategies for achieving them effectively. Establishing career goals brings clarity and purpose to our professional ...

For example, neutrophils regulate ongoing inflammation by modulating ... The CDNPs were labeled with Carboxyfluorescein succinimidyl ester (CFSE) as previously described (10). The CDNP suspension was ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...