11,27 Progression was especially common among those in whom the p.V37I protein was the only connexin 26 protein produced, a population consisting of 11 children homozygous for p.V37I and 7 who ...

The protein Connexin 26 has been previously identified as being directly sensitive to Carbon dioxide and linked to conditions such as KIDS syndrome and deafness. Thanks to a £686,956 grant from ...

In a recent study, the authors have shown that a heterozygous missense mutation, p.R184Q, in the connexin 26 (Cx26 ... and the effect that the mutant protein had on those cells.

The connexin 26 protein coded by the gene is in a family of proteins known as GAP junctions, because these proteins span the tiny gap between cells and form a kind of tube that connects two cells ...

Deafness at birth is often caused by mutations in a specific gene known as Gap Junction Beta 2 (GJB2), which codes for the protein connexin 26. In some populations, mutations of this gene are ...

Defects in this gene lead to the most common form of congenital deafness Everyone has two copies of this gene, but if each birth parent has a flawed copy of the GJB2/Connexin 26 gene, the baby may ...

Mutations to the protein connexin 26 are the most common cause of hearing loss at birth, accounting for more than 25% of genetic hearing loss worldwide. To understand how these mutations lead to ...

A second focus of the Reizes laboratory is on the intercellular communication gap junction protein connexin 26 and its role in cancer stem cells. The connexin proteins are considered tumor suppressor ...

The team studied a protein called connexin 26 (Cx26), which belongs to the connexin class of proteins. While once believed to suppress tumors, recent research suggests that connexins may actually ...

Synchrony between neighboring neurons depends on the protein connexin 36, an essential element of certain types of synaptic connections that, unlike classical chemical synapses, pass signals ...